Description
Product Characteristics:
Aliases: mitochondrial antibody, Selenoprotein Z antibody, SelZ antibody, Thioredoxin reductase 2 antibody, Thioredoxin reductase 2 mitochondrial antibody, Thioredoxin reductase 3 antibody, Thioredoxin reductase beta antibody, Thioredoxin reductase TR3 antibody, TR 3 antibody, TR antibody, TR beta antibody, TR-beta antibody, TR3 antibody, TRXR 2 antibody, TRXR2 antibody, TRXR2_HUMAN antibody, TXNRD 2 antibody, Txnrd2 antibody
Target Information: Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22. [provided by RefSeq, Jul 2008]